hypothalamus – Cell Stress

The role of epigenetics in hypothalamic energy balance control: implications for obesity

INTRODUCTION The prevalence of obesity continues to increase worldwide. This trend is of concern because of its dramatic economic impact, concomitant decreased lifespan and increased comorbidities, such as hypertension, cardiovascular … Read more

Could de-stressing the brain be the solution for long-term weight loss?

INTRODUCTION One just needs to take a look at a typical vending machine (often found in hospitals) to appreciate what has happened to our food and drink. The relatively sudden … Read more

p53 and energy balance: meeting hypothalamic AgRP neurons

Cancer cells undergo profound metabolic changes to cope with the high energy demand for cell growth and division. Given the importance of this metabolic reprogramming in tumor development, it seems … Read more

Astrocytes, emerging stars of energy homeostasis

INTRODUCTION The brain is the organ responsible for the centralized control of the other organs’ functions and, in higher vertebrates, of reasoning. Such tasks are achieved thanks to the interconnections … Read more