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Cell Stress

Journal Impact Factor® 2025: 3.0

CiteScore® 2025: 4.8

Cell Stress
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immunogenic cell death

Inhibitory DAMPs in immunogenic cell death and its clinical implications

– [table id=388/] INHIBITORY DAMP OR INHIBITORY DAMPS? How are immunostimulatory DAMPs shut off? Under normal physiological conditions, the co-stimulatory molecules, CD80/86, on antigen presenting cells bind to the co-activating … Read more

Targeting immune-checkpoint inhibitor resistance mechanisms by MEK inhibitor and agonist anti-CD40 antibody combination therapy

– [table id=351/] IDENTIFYING SUITABLE CYTOSTATIC DRUGS FOR COMBINATORIAL IMMUNOTHERAPY The main dilemma in finding combinations of cytostatic and immunostimulatory drugs that act synergistically is as follows. On the one … Read more

Immune system activation by natural products and complex fractions: a network pharmacology approach in cancer treatment

INTRODUCTION Over the past decade, immunotherapy has become a promising approach to treat cancer and is now being combined with standard chemotherapy and immune response activators to improve the outcome … Read more

Therapeutic anti-tumor immunity directed against neo-epitopes by intratumor delivery of mRNA encoding MLKL

We have developed a potentially generic treatment method to induce tumor antigen-specific cellular immunity based on the transient intra-tumor expression of the necroptosis-inducing factor MLKL (Figure 1). Importantly, we have … Read more

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Keywords

aging Alzheimer’s disease ampk apoptosis autophagy cancer cell death cell stress chemotherapy DNA damage DNA damage response Drosophila drug resistance EMT ER stress gut microbiota hypothalamus immunogenic cell death immunotherapy inflammation innate immunity interferon lipotoxicity metabolism metastasis mitochondria mitochondrial dysfunction mitophagy MTORC1 necroptosis neurodegeneration Nrf2 obesity oxidative stress p53 PD-L1 senescence spermidine stress T cells tfeb therapy tumor microenvironment unfolded protein response

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