Volume 9 (2025)

NFAT5: a stress-related transcription factor with multiple functions in health and disease

Alfredo Domínguez-López1,2, Fátima Sofía Magaña-Guerrero2, Beatriz Buentello-Volante2, Óscar Vivanco-Rojas1,2, Yonathan Garfias1,2

For full text please see the pdf.

Probiotics and mediterranean diet for breast cancer management and prevention?

Ehssan A. Sharif-Askari1, Khadija M. Atoui1, Ali K. Mteyrek2, Lama M. Fawaz3

The human gut microbiota, a diverse community of beneficial normal flora microorganisms, significantly influences physiological function and the immune response. Various microbiota strains have shown promise in supporting clinical treatment of chronic diseases, including cancer, by potentially providing antioxidative and anti-tumorigenic effects in both in vivo and in vitro studies. Breast cancer, which ranks amongst the top five cancer types common worldwide and particularly in Mediterranean countries, has been showing high incidence and prevalence. In breast cancer, microbiota composition, hormonal dynamics, and dietary choices are believed to play significant roles. Hence, the Mediterranean diet, known for its microbiota-friendly features, emerges as a potential protective factor against breast cancer development, highlighting the potential for personalized dietary strategies in cancer prevention. This comprehensive review highlights the emerging mechanisms by (...)

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Bax- Bcl-xL interaction dynamics during the progression of cell cycle and cell death using FLIM-FRET

Aman Munirpasha Halikar1,2, Aneesh Chandrasekharan1, Asha Lekshmi1, Aswathy Sivasailam1, Jain Tiffee P J1,2, Shivanshu Kumar Tiwari1,2, Aijaz Ahmad Rather1,2 and TR Santhoshkumar1

For full text please see pdf.

Nrf1 acts as a highly-conserved determinon for maintaining robust redox homeostasis in the eco-evo-devo process of life histories

Yiguo Zhang1,2,*, Xi Chen1, Meng Wang1, Yuping Zhu1,3, Wei Shi4,5,6, Chao Li4,5,6, Zhengwen Zhang7, Hiroaki Taniguchi8,9 and Ping Ao10

For full text please see pdf.

Pathogenic aspects of fructose consumption in metabolic dysfunction-associated steatotic liver disease (MASLD): A narrative review

Katharina Burger1, Michael Trauner2 and Ina Bergheim1

NFAT5: a stress-related transcription factor with multiple functions in health and disease

Alfredo Domínguez-López1,2, Fátima Sofía Magaña-Guerrero2, Beatriz Buentello-Volante2, Óscar Vivanco-Rojas1,2, Yonathan Garfias1,2

For full text please see the pdf.

Probiotics and mediterranean diet for breast cancer management and prevention?

Ehssan A. Sharif-Askari1, Khadija M. Atoui1, Ali K. Mteyrek2, Lama M. Fawaz3

The human gut microbiota, a diverse community of beneficial normal flora microorganisms, significantly influences physiological function and the immune response. Various microbiota strains have shown promise in supporting clinical treatment of chronic diseases, including cancer, by potentially providing antioxidative and anti-tumorigenic effects in both in vivo and in vitro studies. Breast cancer, which ranks amongst the top five cancer types common worldwide and particularly in Mediterranean countries, has been showing high incidence and prevalence. In breast cancer, microbiota composition, hormonal dynamics, and dietary choices are believed to play significant roles. Hence, the Mediterranean diet, known for its microbiota-friendly features, emerges as a potential protective factor against breast cancer development, highlighting the potential for personalized dietary strategies in cancer prevention. This comprehensive review highlights the emerging mechanisms by (...)

Previous

Role of mitochondrial dysfunction in ocular surface diseases

Xiaohan Chen1, Jiaxu Hong2,3,4,5 and Qihua Le1,3

For full text please see pdf.

Nrf1 acts as a highly-conserved determinon for maintaining robust redox homeostasis in the eco-evo-devo process of life histories

Yiguo Zhang1,2,*, Xi Chen1, Meng Wang1, Yuping Zhu1,3, Wei Shi4,5,6, Chao Li4,5,6, Zhengwen Zhang7, Hiroaki Taniguchi8,9 and Ping Ao10

For full text please see pdf.

Pathogenic aspects of fructose consumption in metabolic dysfunction-associated steatotic liver disease (MASLD): A narrative review

Katharina Burger1, Michael Trauner2 and Ina Bergheim1

NFAT5: a stress-related transcription factor with multiple functions in health and disease

Alfredo Domínguez-López1,2, Fátima Sofía Magaña-Guerrero2, Beatriz Buentello-Volante2, Óscar Vivanco-Rojas1,2, Yonathan Garfias1,2

For full text please see the pdf.

Probiotics and mediterranean diet for breast cancer management and prevention?

Ehssan A. Sharif-Askari1, Khadija M. Atoui1, Ali K. Mteyrek2, Lama M. Fawaz3

The human gut microbiota, a diverse community of beneficial normal flora microorganisms, significantly influences physiological function and the immune response. Various microbiota strains have shown promise in supporting clinical treatment of chronic diseases, including cancer, by potentially providing antioxidative and anti-tumorigenic effects in both in vivo and in vitro studies. Breast cancer, which ranks amongst the top five cancer types common worldwide and particularly in Mediterranean countries, has been showing high incidence and prevalence. In breast cancer, microbiota composition, hormonal dynamics, and dietary choices are believed to play significant roles. Hence, the Mediterranean diet, known for its microbiota-friendly features, emerges as a potential protective factor against breast cancer development, highlighting the potential for personalized dietary strategies in cancer prevention. This comprehensive review highlights the emerging mechanisms by (...)

Burning fat with cysteine depletion

Brittney Adams1, Stanislaw Walkowiak1 and Mohammed K Hankir1

Adams and colleagues comment on two complementary articles by Varghese et al and Lee et al showing that cysteine depletion through combined dietary and genetic means in mice evokes a unique stress response in the liver to amplify these metabolic outcomes and offer a potentially new treatment option for obesity.