Copper – a novel stimulator of autophagy
In biomedicine, the transition metal copper has a Janus-faced dual role, as an essential but static cofactor of vital enzymes but also as a highly detrimental poison, if in excess. … Read more
ULK1
p38β MAPK mediates ULK1-dependent induction of autophagy in skeletal muscle of tumor-bearing mice
INTRODUCTION Cancer has been increasingly recognized as a systemic disorder that stresses multiple organs independent of its location. At least 50% of cancer patients experience cachexia, a systemic wasting syndrome … Read more