PINK1

New insight into the role of autophagy in tumorigenesis

TP53, commonly known as p53, is an important tumor suppressor. Its increased expression was observed not only in the liver tumors of our Atg5-knockout mice but also in the lung … Read more

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aging Alzheimer’s disease ampk apoptosis autophagy cancer cell death cell stress chemotherapy DNA damage DNA damage response Drosophila drug resistance EMT ER stress gut microbiota hypothalamus immunogenic cell death immunotherapy inflammation innate immunity interferon lipotoxicity metabolism metastasis mitochondria mitochondrial dysfunction mitophagy MTORC1 necroptosis neurodegeneration Nrf2 obesity oxidative stress p53 PD-L1 senescence spermidine stress T cells tfeb therapy tumor microenvironment unfolded protein response

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