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Cell Stress

Journal Impact Factor® 2025: 3.0

CiteScore® 2025: 4.8

Cell Stress
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mitochondrial quality control

Mitochondria organize the cellular proteostatic response and promote cellular senescence

Timely disposal and degradation of misfolded proteins and their aggregates is critical for cellular proteostasis and the well-being of a cell. During evolution, cells have acquired a sophisticated system to … Read more

Novel role of the SIRT4-OPA1 axis in mitochondrial quality control

Aging is defined by various molecular and cellular hallmarks, among them stem cell exhaustion, genomic instability, altered proteostasis, cellular senescence, and mitochondrial dysfunction [cite]10.1016/j.cell.2013.05.039[/cite]. Mitochondrial defects are considered major drivers … Read more

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Keywords

aging Alzheimer’s disease ampk apoptosis autophagy cancer cell death cell stress chemotherapy DNA damage DNA damage response Drosophila drug resistance EMT ER stress gut microbiota hypothalamus immunogenic cell death immunotherapy inflammation innate immunity interferon lipotoxicity metabolism metastasis mitochondria mitochondrial dysfunction mitophagy MTORC1 necroptosis neurodegeneration Nrf2 obesity oxidative stress p53 PD-L1 senescence spermidine stress T cells tfeb therapy tumor microenvironment unfolded protein response

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