immune tolerance

Targeting LRH-1/NR5A2 to treat type 1 diabetes mellitus

The liver receptor homolog-1 (LRH-1) is a member of the NR5A family of nuclear receptors that plays a pivotal role in early embryonic development while later on it specifies the … Read more

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aging Alzheimer’s disease ampk apoptosis autophagy cancer cell death cell stress chemotherapy DNA damage DNA damage response Drosophila drug resistance EMT ER stress gut microbiota hypothalamus immunogenic cell death immunotherapy inflammation innate immunity interferon lipotoxicity metabolism metastasis mitochondria mitochondrial dysfunction mitophagy MTORC1 necroptosis neurodegeneration Nrf2 obesity oxidative stress p53 PD-L1 senescence spermidine stress T cells tfeb therapy tumor microenvironment unfolded protein response

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