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Cell Stress

Journal Impact Factor® 2025: 3.0

CiteScore® 2025: 4.8

Cell Stress
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cardiovascular disease

Multifaceted role of CNPY2 beyond ER stress: Disease implications and therapeutic potential

This review meticulously dissects CNPY2’s structural characteristics, expression patterns, and biological functions across various disorders, emphasizing its role on tumor initiation, microenvironmental stress, and chemoresistance, and evaluating its potential as a therapeutic target.

Volume

Article Type

  • Admin
  • Commentary
  • Research
  • Review

Keywords

aging Alzheimer’s disease ampk apoptosis autophagy cancer cell death cell stress chemotherapy DNA damage DNA damage response Drosophila drug resistance EMT ER stress gut microbiota hypothalamus immunogenic cell death immunotherapy inflammation innate immunity interferon lipotoxicity metabolism metastasis mitochondria mitochondrial dysfunction mitophagy MTORC1 necroptosis neurodegeneration Nrf2 obesity oxidative stress p53 PD-L1 senescence spermidine stress T cells tfeb therapy tumor microenvironment unfolded protein response

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