Fumarase mediates transcriptional response to nutrient stress

Authors:

Qin Zhao1 and Yuhui Jiang1
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Affiliations:

1 The Institute of Cell Metabolism, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai 200080, China.

Keywords: 

fumarase, cellular response, nutrient condition.

Corresponding Author(s):

Yuhui Jiang, The Institute of Cell Metabolism, Shanghai Key Laboratory of Pancreatic Disease, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai 200080, China yhjiang@shsmu.edu.cn

Conflict of interest statement:

No potential conflicts of interest were disclosed.

Please cite this article as:

Qin Zhao, Yuhui Jiang (2017). Fumarase mediates transcriptional response to nutrient stress. Cell Stress 1(1): 68-69. doi: 10.15698/cst2017.10.107

© 2017 Zhao and Jiang. This is an open-access article released under the terms of the Creative Commons Attribution (CC BY) license, which allows the unrestricted use, distribution, and reproduction in any medium, provided the original author and source are acknowledged.

Abstract:

Limited supply of nutrient normally causes cell growth arrest. Our recent study (Nat Cell Biol. (7):833-843) shows that fumarase (FH), a key enzyme responsible for the conversion between fumarate and malate in tricarboxylic acid cycle, is importantly involved in the cellular response to nutrient condition.