Gut microbiota turn up the heat after bariatric surgery

Authors:

Mohammed K. Hankir1
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Affiliations:

1 Department of General, Visceral, Transplantation, Vascular and Pediatric Surgery, University Hospital Wuerzburg, Wuerzburg, Germany.

Keywords: 

vertical sleeve gastrectomy, Roux-en-Y gastric bypass, gut microbiota, thermogenesis, obesity, Type 2 diabetes.

Corresponding Author(s):

Mohammed K. Hankir, Center of Operative Medicine, Oberduerrbacherstr. 6, 97080 Wuerzburg, Germany; hankir_m@ukw.de

Conflict of interest statement:

The author has no conflicts of interest to declare.

Please cite this article as:

Mohammed K. Hankir (2023). Gut microbiota turn up the heat after bariatric surgery. Cell Stress 7(10): 90-94. doi: 10.15698/cst2023.10.290

© 2023 Hankir et al. This is an open-access article released under the terms of the Creative Commons Attribution (CC BY) license, which allows the unrestricted use, distribution, and reproduction in any medium, provided the original author and source are acknowledged.

Abstract:

Bariatric surgeries like vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB) cause well-established shifts in the gut microbiota, but how this contributes to their unique metabolic benefits is poorly understood. Jin et al and Yadav et al now provide two complementary lines of evidence suggesting that gut microbiota-derived metabolites after VSG and RYGB activate thermogenesis in fat through distinct mechanisms, to in turn promote weight loss and/or improvements in glycemic control.