PDLIM1: Structure, function and implication in cancer

Affiliations:

¹ Laboratory of Molecular Oncology, Frontiers Science Center for Disease-related Molecular Network, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.

² Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu 610041, China.

Keywords: 

PDLIM1, CLP36, cytoskeleton, EMT, cancer progression.

Abbreviatons:

AA – amino acid;

ACTN – α-actinin;

ALP – actinin-associated LIM protein;

Clik1 – CLP-36 interacting kinase 1;

CLP36 – carboxyl terminal LIM domain protein of 36 kDa;

CML – chronic myelogenous leukaemia;

CRC – colorectal cancer;

DRG – dorsal root ganglion;

EMT – epithelial-mesenchymal transition;

ES – ectoplasmic specialization;

HCC – hepatocellular carcinoma;

neoHFF – neonatal human foreskin fibroblasts;

PDLIM1 – PDZ and LIM domain protein 1;

RIL – reversion-induced LIM protein.

Corresponding Author(s):

Conflict of interest statement:

The authors declare no conflict of interest.

Please cite this article as:

Jian-Kang Zhou, Xin Fan, Jian Cheng, Wenrong Liu and Yong Peng (2021). PDLIM1: Structure, function and implication in cancer. Cell Stress 5(8): 119-127. doi: 10.15698/cst2021.08.254

© 2021 Zhou et al. This is an open-access article released under the terms of the Creative Commons Attribution (CC BY) license, which allows the unrestricted use, distribution, and reproduc-tion in any medium, provided the original author and source are acknowledged.