Role of RNA Binding Proteins with prion-like domains in muscle and neuromuscular diseases

Affiliations:

¹ Université de Strasbourg, INSERM, Mécanismes Centraux et Périphériques de la Neurodégénérescence, UMR_S 1118, Strasbourg, France.

Keywords: 

RNA-Binding Protein (RBP), Muscle, Dystrophy, Amyotrophic lateral sclerosis (ALS), Spinal muscular atrophy (SMA), Inclusion body myopathy (IBM), Fragile X-associated tremor / ataxia syndrome (FXTAS), Multisystem proteinopathy (MSP), Huntington’s disease.

Abbreviatons:

AchR – acetylcholine receptor;

ALS – amyotrophic lateral sclerosis;

FTD – fronto-temporal dementia;

hnRNP – heterogenous nuclear ribo-nucleoprotein;

IBM – Inclusion body myositis;

NMJ – neuromuscular junction;

OPMD – oculopharyngeal muscular dystrophy;

PrLD – prion-like domain;

RBP – RNA binding protein;

RGG – Arginine-Glycine-Glycine rich domain;

SMA – spinal muscular atrophy;

SMN – survival of motor neurons.

Corresponding Author(s):

Conflict of interest statement:

The authors declare no conflict of interest.

Please cite this article as:

Gina Picchiarelli and Luc Dupuis (2020). Role of RNA Binding Proteins with prion-like domains in muscle and neuro-muscular diseases. Cell Stress 4(4): 76-91. doi: 10.15698/cst2020.04.217

© 2020 Picchiarelli and Dupuis. This is an open-access article released under the terms of the Creative Commons Attribution (CC BY) license, which allows the unrestricted use, distribution, and reproduc-tion in any medium, provided the original author and source are acknowledged.