Immunosurveillance of cancer cell stress

Affiliations:

¹ Departamento de Biología Funcional, Inmunología, Universidad de Oviedo, Oviedo, Spain.

² Instituto Universitario de Oncología del Principado de Asturias (IUOPA) Oviedo, Spain.

³ Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain.

Keywords: 

cancer, cell stress, immune system, tumor immunity, immunosurveillance.

Abbreviatons:

ATM – ataxia-telangiectasia mutated,

CML – chronic myelogenous leukemia,

CRT – calreticulin,

DC – dendritic cell,

DDR – DNA damage response,

ER – endoplasmic reticulum,

GZMB – granzyme B,

HIF – hypoxia-inducible factor,

HRE – hypoxia response element,

HSF – heat shock transcription factor,

HSP – heat shock protein,

ICB - immune checkpoint blockade,

IFNγ – interferon γ, LLC – Lewis lung carcinoma,

MDSC – myeloid-derived suppressor cell,

MHC – major histocompatibility complex,

MICA – MHC class I polypeptide-related sequence,

MM – multiple myeloma,

mTOR – mammalian target of rapamycin,

NK – natural killer,

ROS – reactive oxygen species,

TAM – tumor-associated macrophage,

TME – tumor microenvironment,

Treg – regulatory T cell,

UPR – unfolded protein response,

VEGF – vascular endothelial growth factor.

Corresponding Author(s):

Conflict of interest statement:

The authors declare no conflict of interest.

Please cite this article as:

Seila Lorenzo-Herrero, Christian Sordo-Bahamonde, Segundo González and Alejandro López-Soto (2019). Immunosur-veillance of cancer cell stress. Cell Stress 3(9): 295-309. doi: 10.15698/cst2019.09.198

© 2019 Lorenzo-Herrero et al. This is an open-access article released under the terms of the Creative Commons Attribution (CC BY) license, which allows the unrestricted use, distribution, and re-production in any medium, provided the original author and source are acknowledged.