Necroptosis, tumor necrosis and tumorigenesis

Affiliations:

¹ Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute; National Institutes of Health, 37 Convent Drive, Bethesda, MD 20892.

Keywords: 

necroptosis, tumor necroptosis, tumorigenesis, tumor metastasis, inflammation, and immunosuppression.

Abbreviations:

ADAM – A Disintegrin And Metalloproteases,

Casp-8 – caspase 8,

CXCL – (C-X-C motif) ligand,

IFN – interferon,

MAP – mitogen activated protein,

MDSC – myeloid-derived suppressor cell,

Mincle – macrophage inducible Ca2+-dependent lectin receptor,

MLKL – mixed lineage kinase domain-like,

PDA – pancreatic ductal adenocarcinoma,

RHIM – RIP Homotypic Interaction Motif,

RIPK – receptor interacting protein kinase,

SAP-130 – 130 kDa Sin3-associated polypeptide,

sE-Cadherin – soluble E-Cadherin,

TLR – toll-like receptor,

TNF – tumor necrosis factor,

ZBP – Z-DNA- binding protein.

Corresponding Author(s):

Conflict of interest statement:

No conflict of interest exists.

Please cite this article as:

Zheng-gang Liu and Delong Jiao (2019). Necroptosis, tumor necrosis and tumorigenesis. Cell Stress 4(1): 1-8. doi: 10.15698/cst2020.01.208

© 2019 Liu and Jiao. This is an open-access article released under the terms of the Creative Commons Attribution (CC BY) license, which allows the unrestricted use, distribution, and reproduction in any medium, provided the original author and source are acknowledged.