Mitochondrial stress delays tumorigenesis in a Li-Fraumeni syndrome mouse model

Authors:

Matthew P. Donnelly1, Jie Li1 and Paul M. Hwang1
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Affiliations:

1 Cardiovascular Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.

Keywords: 

p53, mitochondria, Li-Fraumeni syndrome, mouse model, cyclin D1, DNA polymerase gamma, metformin.

Corresponding Author(s):

Paul M. Hwang, NHLBI, National Institutes of Health, Bethesda, Maryland, USA hwangp@mail.nih.gov

Conflict of interest statement:

The authors declare that they have no conflict of interests.

Please cite this article as:

Matthew P. Donnelly, Jie Li and Paul M. Hwang (2019). Mitochondrial stress delays tumorigenesis in a Li-Fraumeni syndrome mouse model. Cell Stress 3(4): 115-117. doi: 10.15698/cst2019.04.182

© 2019 Donnelly et al. This is an open-access article released under the terms of the Creative Commons Attribution (CC BY) license, which allows the unrestricted use, distribution, and reproduction in any medium, provided the original author and source are acknowledged.

Abstract: