Structure image from the RCSB PDB (rcsb.org) of PDB-ID 1CX2 (Kurumbail et al, 1997) Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. Nature 384: 644-648. Backdrop image: Growing cancer cells spreading to other parts of the body through the circulatory system. Credit: Darryl Leja, National Human Genome Research Institute, NIH. Public domain image modified by Cell Stress. The cover is published under the CC BY 4.0 license.