This month in Cell Stress: Protein methyl transferases in cancer. Crystal structure of the human PRMT5:MEP50 complex. PDB-entry 4GQB by Antonysamy et al. (doi:10.2210/pdb4GQB/pdb). Backdrop shows H&E staining of invasive breast cancer cells (Public domain image by Dr. Cecil Fox). Image modified by Cell Stress. The cover is published under the CC BY 4.0 license.