Michael A Mandell

University of New Mexico (USA)

Dr. Mandell’s laboratory investigates how the autophagy machinery impacts cellular inflammatory responses. In particular, Dr. Mandell is interested in the actions of tripartite motif containing protein family members (TRIMs). Dysregulation of TRIMs is associated with several inflammatory diseases and multiple cancers. Dr. Mandell’s studies have demonstrated that the regulation of selective autophagy is a conserved and important function of this large protein family. ​