Harald Steiner

Germany German Center for Neurodegenerative Diseases (Germany)

He has a long-standing interest in understanding the functions and mechanism of γ-secretase. This enzyme is a pivotal intramembrane protease, which has a wide spectrum of substrates and is implicated in many crucial signaling pathways. A major focus of his work is to understand how the enzyme generates the amyloid-β peptide, which is widely believed to be causative for Alzheimer´s disease.