Volker Haucke

Leibniz Institut für Molekulare Pharmakologie Berlin (Germany) 

The focus of research in the Haucke laboratory is the dissection of the molecular mechanisms of endocytosis and endolysosomal membrane dynamics and its role in nutrient and growth factor signaling, development of the nervous systems and in neurotransmission. The laboratory uses a wide range of technologies that include biochemical and molecular biological approaches in vitro, chemical biology and screening technology, super-resolution and electron microscopy as well as genetic manipulations at the organismic level in vivo. The overarching goal of our studies is to provide a mechanistic understanding of exo-endocytosis and endolysosomal function and its regulation by proteins and lipids in cell physiology and to use this know-how to develop novel strategies for acute chemical and pharmacological interference.