Back to article: Regulation of immune checkpoint blockade efficacy in breast cancer by FIP200: A canonical-autophagy-independent function
FIGURE 1: The canonical-autophagy-independent function of FIP200 regulates TBK1 activation, chemokine production, T-cell infiltration and immune checkpoint inhibitor efficacy. Schematic summarizing the phenotypes observed upon the loss of FIP200's canonical-autophagy-independent function and a working model of this regulatory process.