Back to article: Mechanisms and therapeutic significance of autophagy modulation by antipsychotic drugs


Table 1. Modulation of neuronal/brain autophagy by antipsychotics.

“Flux” refers to autophagic flux; ↑ denotes increase/activation; ↓ denotes de-crease/inhibition; n.a. – not assessed; AMPK – AMP-activated protein kinase; ATG – autophagy related; DA – dopaminergic; PINK1 – Phosphatase and tensin homolog -induced kinase 1; ROS – reactive oxygen species; TDP43 – TAR DNA-binding protein 43; TFEB – transcription factor EB; ULK1 – Unc-51 like autophagy activating kinase.

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